Nanobiosensors for Antimicrobial Resistance Surveillance: Possibilities and Challenges

Antimicrobial resistance (AMR) is a pressing global health concern, causing the spread of antibiotic-resistant bacteria and genes. Traditional methods, such as culture-based techniques and molecular assays, are costly and time-consuming. Nanobiosensors, a hybrid instrument combining nanomaterials with biological recognition elements, offer a scalable, precise detection method. This chapter explores the molecular basis of resistance mechanisms, the limitations of traditional detection methods, and the critical components of nanobiosensors. It also discusses the challenges and limitations of this promising technology for AMR detection and management.